Desequilibradas translates to "unbalanced" or "uneven". It's a descriptive word that goes beyond simple emotions to explain a complex situation.
In the song, Adriel Favela uses it to describe the unequal effort in a relationship: "Las cosas fueron desequilibradas" (Things were unbalanced). He gave everything, while his partner gave nothing, making this word a poignant summary of the song's central theme of one-sided love.
"En Este Amor" ("In This Love") is about a relationship where only one person kept trying.
The singer says he gave everything he had, tried again and again, and still couldn't make it work. He admits the love was unbalanced from the start: he gave more than he had, while the other person gave nothing back.
Now he accepts that he has to be the one to let go. Life moves on for the other person either way, but in this love, one side dies while the other lives on unaffected.