Jale is a very common slang word for "work" or "job" in Mexican Spanish, derived from the verb jalar (to pull).
In the song, Peso Pluma sings, "Cosas del jale que no entiende nadie" (Things from the job that nobody understands). He uses this word to add a mysterious and informal tone, hinting that his line of work is secretive and maybe even dangerous, a central theme in his music.
Peso Pluma kicks this song off by talking directly to God, which is a bold move. He says, "Dios, no quería desvelarme, y aquí ando en el desmadre" (God, I didn't want to stay up late, and here I am in this mess). He's in the middle of a wild scene where he can't even feel the effects of drugs or alcohol anymore, but he's also thinking about his mom's prayers. It's this constant back-and-forth between a dangerous lifestyle and his faith that makes the song so compelling.
He talks about "Cosas del jale que no entiende nadie" (Things from the job that nobody understands), suggesting a secret, misunderstood line of work. The most intense image is when he says, "Me escondo el rosario bajo de la camiseta para envenenarme" (I hide the rosary under my shirt to poison myself). He keeps his faith physically close but hidden while doing things he knows are wrong. He seems convinced he'll be forgiven by "el jefe" (the boss), which could mean God or a more literal boss. It's a look inside the head of someone living a life of contradictions, trying to balance sin and salvation.