ゾロ目 refers to a number whose digits are all the same, such as 111, 777, or 999. It is a catchy Japanese term with a playful, lucky feeling, and it appears in the song as something the bassist absolutely adores, making it an unusually memorable detail.
The first verse of "What's Up!" is a band roll call, and it is affectionate and a little mean. The bassist is "強気なやんちゃベーシスト" [a cocky, mischievous bassist] who talks baby talk to his pet: "ペットには「でちゅまちゅ」言葉" [with his pet he uses "dechu machu" words]. "でちゅまちゅ" is the cutesy lisp version of the polite endings です and ます, the way someone coos at a puppy. The drummer is "几帳面でハデなドラマー" [a neat-freak, flashy drummer] who "ゾロ目をこよなく愛す" [adores matching numbers], meaning repeated digits like 7:77 or 11:11. The guitarist plays it cool, "やっぱりギャグもcoolで" [and of course even his jokes are cool], and the shy pianist is "以外とキレると恐い" [surprisingly scary when he snaps]. It is an inside joke set to a pop-rock tune, and that is the fun of it.
Then the singer turns to the listener. He hopes this goes on forever, "まじめにバカやり続けながら" [seriously keep on fooling around], and admits the band is aging: "ハジけてもそろそろミドル" [we may go wild, but we're nearly middle-aged] and "若い子には勝てなくて" [we can't beat the young kids]. The "君" [you] here reads like a fan: "浮気性の君だけど" [you're the fickle type] and "目移り時々にしてね" [only let your eye wander sometimes, okay?]. That is a cheeky plea not to drift off to other bands. The chorus asks "笑ってずっとそばにいて" [smile and stay by my side forever], because "まだ君が必要だから" [we still need you].