Loquerón is a colloquial and intensified form of locura (madness or craziness). It refers to a prolonged period of wild partying, excessive behavior, or a crazy spree.
In the song, the artist uses loquerón to describe a lifestyle filled with constant partying, women, and indulgence, often as a way to cope with heartbreak. It's a vivid and culturally specific term that captures the essence of the song's narrative.
Gabito Ballesteros kicks off this song with a wild scene of parties and excess. He's living it up with whiskey, expensive clothes, and lots of women, admitting he's "perdido en la fama" (lost in fame). He's smoking so much weed he has "los ojos bien rojos por la marihuana" (eyes all red from the marijuana). It sounds like a great time, but the whole mood flips when he reveals what's really going on.
This whole party lifestyle is his way of dealing with a brutal breakup. He tells his ex that after she left, "la pasé culero" (I had a terrible time). He felt he gave her everything, even promising the stars, but she "querías otra vida" (wanted another life). Now, his friends are tired of his behavior, calling it "un loquerón de más" (one more crazy binge). He's trying to convince himself he's over it, insisting "Con otro amor te voy a olvidar" (I'm going to forget you with another love), but it's clear the pain is still there.