Hipo literally translates to "hiccups". It's a fun and somewhat unusual word to find as a central theme in a song, making it instantly memorable.
In "El Hipo," Danny Romero uses the word playfully to describe the overwhelming effect someone has on him. He sings, "Me quita el hipo-po-po," meaning this person is so captivating that they literally make his hiccups disappear. It's a creative and endearing way to express being completely smitten.
"El Hipo" ("The Hiccup") turns being smitten into a physical symptom. Danny Romero opens locked on someone's eyes: "Mírame a los ojos que no sé vivir" (Look me in the eyes, I don't know how to live), "No sé respirar sin ti" (I can't breathe without you) — classic lovesick hyperbole before the song gets specific about what she actually does to him: "Me quita el hipo-po-po" (She gives me the hiccups), "Me tiene loco-co-co del coco-co-co" (She's got me crazy in the head). The stuttered "po-po-po" and "co-co-co" mimic an actual hiccup, turning the chorus into a little vocal joke as much as a lyric.
Juan Magan's verse keeps the fever going — "Como un veneno en el cuerpo metido" (Like a poison stuck in my body) — before the song lands on its real request: "Un beso me sabe a poco" (One kiss isn't enough for me), "Ay, dame otro, otro y otro" (Give me another, another, and another). It's a light, danceable reggaeton-pop track built entirely around one running gag: attraction as an involuntary, slightly ridiculous physical reflex.