Endrogo comes from the verb endrogarse, a slang term meaning 'to drug oneself' or 'to get high'. It is not a word you'll find in every song, making it uniquely tied to this track's central metaphor.
Daddy Yankee uses it in the line "Yo me endrogo de ti y te desvisto" to express an intense, almost chemical addiction to his lover. Instead of a literal drug, he gets high on her presence and the act of undressing her, perfectly capturing the song's theme of uncontrollable desire.
Daddy Yankee and Anuel AA are not messing around in this song. "Adictiva" is all about a physical connection so intense it feels like a powerful drug. The singers can't get this person out of their minds, comparing them to a vice: "Yo no me pienso quitar, tú eres mi vicio" (I don't plan on quitting, you are my vice). They feel desperate and hooked, left wanting more after just one encounter.
The whole song uses the language of addiction to describe this obsession. They talk about needing an overdose, feeling sick without her, and even going through withdrawal, saying "me tienes rompiendo en frío" (you have me going through cold turkey). They are very clear that this isn't about love—"Yo se que tú a mí no me amas / Pero mi cuerpo te llama" (I know you don't love me / but my body calls you). It's a blunt and fiery description of pure, overwhelming desire.