Masoquismo translates to "masochism," which is the enjoyment of an activity that appears to be painful or tedious.
In the song, the artist describes a relationship caught in a cycle of negativity, where the same problems repeat. He sings about "el mismo pesimismo combinado con masoquismo" (the same pessimism combined with masochism), suggesting that despite the pain, there's a subconscious draw to the dysfunctional dynamic. This word adds a psychological depth to the lyrics, making it quite intriguing.
Have you ever been stuck in a relationship you know isn't good for you, but you just can't seem to leave? That's exactly where Yandel is in "No Se." He's caught in a frustrating cycle, feeling like his partner is playing games with his mind: "Mucho juegas con mi mente, Tú me ganas y me pierdes" [You play a lot with my mind, You win me and you lose me]. He sees their relationship as a dead end, saying "Lo nuestro no lo veo, Así no lo veo" [I don't see our thing, I don't see it like that].
Even though he's decided to break up, he admits he still might give in if she invites him into her room: "Ya tome la decisión, no sé, no sé, No sé, tal vez me hagas la invitación De entrar a la habitación Volver a ti, no sé" [I already made the decision, I don't know, I don't know, I don't know, maybe you'll invite me to enter the room, to go back to you, I don't know]. He describes their dynamic as a "masochism" and feels like they're two different worlds that only make sense when they're alone. It's a really honest look at how hard it can be to break free from a toxic connection, even when you know it's for the best.