Veneno literally translates to "poison". It's a dramatic and powerful word that immediately grabs your attention.
In the song, the singer uses it metaphorically to describe the painful aftermath of a breakup. He sings, "Se fue la dulce miel que probé en sus labios / Se fue, me quedó sólo su veneno" (The sweet honey I tasted on her lips is gone / She left, I'm left only with her poison). This stark contrast between "honey" and "poison" vividly illustrates how a love that was once sweet and life-giving has become toxic and painful.
This song is a duet about a devastating breakup, told from both sides. It's a remake of a classic 90s pop ballad by Italian singer Laura Pausini, but Puerto Rican superstar Rauw Alejandro gives it a modern reggaeton twist. The song starts with him in total despair because his partner has left. He asks, "¿Por qué de pronto ya no me quería?" (Why did she suddenly not love me anymore?). He feels like everything good is gone, from "el perfume de sus cabellos" (the perfume of her hair) to "la dulce miel que probé en sus labios" (the sweet honey I tasted on her lips). All he has left is "su veneno" (her poison) and a love that's been "cubrió de hielo" (covered in ice).
Then, Laura Pausini comes in with her side of the story, and it turns out she's just as heartbroken. She feels her world has been destroyed, saying "En mi verano ya no sale el sol" (In my summer the sun no longer rises). She's so lost without him that she feels he has become the "centro / Y fin de todo mi universo" (center / And end of my whole universe). They both feel like their lives are over without the other person, but neither seems to know why it ended. The song just repeats the phrase "Se fue y la razón no la sé" (She/He left and I don't know the reason), leaving us with the mystery of a love that was clearly intense but somehow fell apart.