Guagua is a colloquial term for 'bus' in several Latin American countries, particularly in Cuba and the Caribbean, where Gente de Zona is from. It's a fun and unique word that isn't commonly heard in all Spanish-speaking regions.
In the song, the lyrics mention "coger la gua-gua-gua sin GPS" (take the bus without GPS), highlighting a more down-to-earth mode of transport compared to the luxurious items like a Lamborghini mentioned elsewhere. This contrast makes the word stand out and offers a glimpse into Cuban slang.
Gente de Zona bring in Zurdo MC and Wow Popy for a track that's basically one long flex, and it opens by naming everybody right away: "Oye, Zurdo MC" (Listen, Zurdo MC), "Wow, Poppy, el loco" (Wow, Poppy, the crazy one). Zurdo MC spends his verse making it clear nobody's bringing him down: "No tienen pa' tumbarme" (They don't have enough to take me down), "y a partir de ahora hay que aguantarme" (and from now on you've got to put up with me). Everything after that is the receipts: a Lamborghini, dressing in AMIRI all day, telling Siri and Alexa not to even bother because whatever it costs, he's paying it.
The hook is where the title comes from: "A coger la gua-gua-gua sin GPS, GPS" (To grab the bus-bus-bus without GPS, GPS), riding without needing directions because they already know exactly where they're going. By the bridge even the group sounds a little surprised at their own run: "Los junté, funcionó" (I put them together, it worked), looking back at how far Gente de Zona has come "con la nueva escuela" (with the new school). It's less a love song than a victory lap, and it knows it.