Calibre 50 is a Regional Mexican band founded in the city of Mazatlán, Sinaloa in 2010. Their style is Norteño-Banda, a hybrid of Norteño, which uses an electric bass or tololoche for the low notes and replaces it with a sousaphone (tuba), which is typically used in Banda for the bass notes. Calibre 50 first achieved notoriety for their controversial songs; among them corridos. Their first nationwide hit was "El tierno se fue" ("The nice guy is gone") in 2011, a ranchera written by Lalo Ayala which contains many sexual innuendos. Throughout its history, the band has recorded different styles of songs such as rancheras, corridos, ballads, cumbias, charangas, boleros, and huapangos. In March 2017, Calibre 50 made history when the band became the first Regional Mexican act to perform on the Conan show on an episode that took place in Mexico City. In 2023, they held a record with 23 No. 1 songs on the Billboard Regional Mexican Airplay chart.