"Que Locura Enamorarme De Ti" by Eddie Santiago is a song about the intense and forbidden love between two people. The narrator expresses his feelings of love and desire for his friend, knowing that her love belongs to someone else. He expresses his longing for her, wishing to show her what true love is and to make her feel the same way he does. Despite the impossibility of their love, he still hopes that one day she will give in to his pleas and they can experience a passionate love affair.

Eddie Santiago is a Puerto Rican salsa singer and songwriter who has been a major force in the Latin music scene since the 1980s. He is known for his passionate and romantic style of singing, which has earned him a loyal fan base throughout Latin America and the United States. Santiago's career took off in 1986 in Puerto Rico and the rest of Latin America as a soloist, recording songs including: "Tú me quemas" ("You Burn Me"), "Qué Locura Enamorarme de Ti" ("What Madness To Fall in Love With You"), "Me Fallaste" ("You Failed Me"), Antidoto y Veneno ("Antidote and Venom"), "Tu Me Haces Falta" ("I Miss You"), "Lluvia" ("Rain"), and many others. Santiago has earned both gold and platinum records, along with other awards. He is one of the main singers of "salsa romántica" ("romantic salsa").